Moderate senators appear likely to support DeVos, meaning she will almost certainly be confirmed. But Democrats are already fundraising off of the controversy surrounding her nomination.
School choice is front-and-center in national debates about education, in large part because of Trump's nominee for education secretary, Betsy DeVos.
Jason Botel's move might surprise some of those who view Trump's education policy through a strictly partisan or conservative lens.
EdWeek reached a handful of Republican teachers and others who voted for President Donald Trump, but oppose Betsy DeVos, his pick for education secretary.
"I believe that all students, including individuals with disabilities, deserve an equal opportunity to lead full, productive and successful lives," DeVos wrote in her Jan. 24 letter to Sen. Johnny Isakson, R-Ga.
President Donald Trump's executive order affecting many federal agencies, with the exception of military employees, could mean longer hours for career staff and slower response to inquiries.
The nominee for education secretary would still need to build bridges in Congress and overcome the skepticism of many in the education community.
The "Blueprint to Rebuild America's Infrastructure and Create 15 Million Jobs" is short on details, but includes a plan to create 975,000 jobs by improving school infrastructure.
Sen. Lamar Alexander, R-Tenn., Sen. Tim Scott, R-S.C., and other GOP lawmakers said they're confident the nominee for education secretary will be confirmed despite opposition from Democrats and others.
There are major questions about what the new administration will mean for everything from the big data sets to the Education Department's more than 4,000 career employees.